* William Henry Gates, his paternal great-grandfather
* Rebecca Eppinhauser, his paternal great-grandmother
o William Henry Gates I, his paternal grandfather
* William H. Rice, his maternal great-grandfather
* Isabella Thompson, his maternal great-grandmother
o Lillian Elizabeth Rice, his paternal grandmother
+ William Henry Gates, Sr., his father
* James Willard Maxwell, his maternal great-grandfather
* Belle Oakley, his maternal great-grandmother
o James W. Maxwell, his maternal grandfather
* William J. Thompson, his maternal grandfather, Adelle Thompson's father
* Ida Medcalf, his maternal grandmother, Adelle Thompson's mother
o Adelle Thompson, his maternal grandmother
+ Mary Maxwell Gates, his mother
# Kristianne Gates Blake, his older sister
* Kerry Adelle Blake, his niece
* Sullivan Michael Blake, his nephew
# Libby Gates Armintrout, his younger sister
* Stephen Maxwell Armintrout, his nephew
* Mary Elizabeth Armintrout, his niece
# William Henry Gates III, commonly known as Bill Gates
# Melinda French Gates, his wife
* Jennifer Katharine Gates, his daughter born in 1996
* Rory John Gates, his son born in 1999
* Phoebe Adelle Gates, his daughter born in 2002
+ Mimi Gardner Gates, second wife of William, Sr.
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